Stabilność komponenta sieciującego warstwę receptorową biosensora po dodaniu nanocząstek złota

pol Artykuł w języku polskim DOI: 10.14313/PAR_239/49

wyślij Aleksandra Kłos-Witkowska , Vasyl Martsenyuk Akademia Techniczno-Humanistyczna w Bielsku-Białej, Wydział Budowy Maszyn i Informatyki, Katedra Informatyki i Automatyki

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Streszczenie

W pracy przeprowadzono badania stabilności składnika warstwy receptorowej biosensora po dodaniu nanocząstek złota. Wykazano przyspieszone zmiany konformacyjne pod wpływem Au. Obliczono względne procentowe zmiany w czasie między czystym białkiem a białkiem domieszkowanym Au. Wykazano, że z czasem zmiany te są większe i przekraczają 20 % w ostatnich dniach eksperymentu.

Słowa kluczowe

biosensor, nanocząstki Au, stabilność

Stability of the Cross Linking Component of the Biosensor Receptor Layer after Addition of Gold Nanoparticles

Abstract

In this study, the stability of the receptor layer component of a biosensor after addition of gold nanoparticles was investigated. Accelerated conformational changes under the influence of Au were demonstrated. The relative percentage changes over time between the pure protein and the Au doped protein were calculated. It was shown that these changes are greater with time and exceed 20 % in the last days of the experiment.

Keywords

Au nanoparticles, biosensor, stability

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